Current status of anti-CD30 monoclonal antibody therapy in anaplastic lymphoma and Hodgkin’s lymphoma

Published: June 10, 2009
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Until the advent of anti-CD20 antibody therapy, the mainstay of treatment in non-Hodgkin’s lymphoma (NHL) was standard chemotherapy. The combination of antibodies with chemotherapy has enhanced event-free and overall survival in both diffuse large B cell NHL and follicular NHL.1 With this example of combined chemo/ immunotherapy to enhance clinical response, it has been considered of interest to attempt a similar approach for T cell NHL and Hodgkin’s lymphoma (HL).

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Proctor, S., & Wilkinson, J. (2009). Current status of anti-CD30 monoclonal antibody therapy in anaplastic lymphoma and Hodgkin’s lymphoma. Hematology Meeting Reports (formerly Haematologica Reports), 2(13). https://doi.org/10.4081/hmr.v2i13.483