Acitretin systemic and retinoic acid 0.1% cream suppression of basal cell carcinoma


Submitted: 5 September 2009
Accepted: 14 December 2009
Published: 16 March 2010
Abstract Views: 5612
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Retinoids have been used for years as monotherapy and/or in combination for treatment and suppression of cutaneous malignancies in patients with basal cell nevus syndrome, xeroderma pigmentosum, or cutaneous T-cell lymphoma (CTCL) basal cell carcinoma (BCC). We report 4 cases with BCC confirmed by histopathology who were treated by short-term systemic acitretin combined with retinoic acid 0.1% cream. The 4 cases with BCC showed good response to the treatment without severe adverse effects during treatment and follow-up. The finding suggests that acitretin may be an appropriate treatment option for elderly patients who require less invasive treatment for BCC.


Zhang, X.-B., Zhang, S.-Q., Li, C.-X., Huang, Z.-M., & Luo, Y.-W. (2010). Acitretin systemic and retinoic acid 0.1% cream suppression of basal cell carcinoma. Dermatology Reports, 2(1), e4. https://doi.org/10.4081/dr.2010.e4

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